Mitotic entry is determined by a threshold level of active cyclin-B1/CDK1 complex, also known as cyclin-B1/Cdc2 or the maturation promoting factor (MPF). Active cyclin-B1/CDK1 triggers irreversible actions in early mitosis, including centrosome separation, nuclear envelope breakdown, and spindle assembly. In vertebrates, there are five cyclin B isoforms (B1, B2, B3, B4, and … WebNov 4, 2013 · Intron retention and cytoplasmic splicing are emerging forms of transcriptional regulation that add to the molecular diversity of mammalian cells. …
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WebFeb 15, 2024 · SUMOylation of SET at K68 induces its cytoplasmic retention. a HEK-293 T cells were co-transfected with Flag-SET-WT, Flag-SET-K68R, His-SUMO-1 and UBC9 plasmids for 48 h. Cells were lysed and ... WebJul 14, 1998 · Here we provide evidence that retention of tsp53 in the cytoplasm at the non-permissive temperature is due to cytoskeletal anchorage of the p53 protein. Two … green class scallop pool table lights
Frontiers Sequence Determinants for Nuclear Retention …
WebOct 4, 1999 · Cytoplasmic retention of Dnmt1 is independent of protein size. Two β-galactosidase fusion constructs were generated, one containing amino acids 1–854 of Dnmt1 (depicted in the diagram, Fig. 4 I) and the other containing amino acids 1–796 of human DNA ligase I (Cardoso et al. 1997). The size of both fusion proteins is between … WebJan 1, 2005 · If the droplet is normally shed then its retention on sperm in the ejaculate may be associated with infertility, and there is considerable evidence that this is the … WebJul 19, 2004 · In this study, we present results about a novel function of tomato Hsp17.4-CII as cytoplasmic retention factor and corepressor of HsfA2. In fact, the functional state and intracellular distribution of HsfA2 is influenced by a network of proteins involving HsfA1, Hsp17-CI, and Hsp17-CII. RESULTS flow pictures